NO Limits
ThalidomideStory.com
is a film about Thalidomide, a drug made by Grünenthal which severely disabled thousands of babies in the 60's and caused the worst pharmaceutical scandal in history.
"NO Limits" A film by John Zaritsky now on Amazon Prime
THALIDOMIDER STORIES
ABOUT THE DRUG THALIDOMIDE
ABOUT GRÜNENTHAL
OTHER NOTABLES
TIMELINE
FILM
RESOURCES
THALIDOMIDER STORIES
Thalidomiders
Alvin Law
Rejected at birth
My life became this life
Why do I need arms?
I love driving!
Building character
This is how I do things
Motivational Speaker
Alvin Law Bio
Eileen Cronin
Four Leaf Clover
Love at first sight
Artificial Limbs
Eileen Cronin Bio
Niko von Glasow
A timid child
Becoming a director
Time to look the devil in the asshole
Nobody's Perfect
The most important thing
It's good to be rich!
Niko von Glasow Bio
Louise Mason
Growing Up
Bullying
Marriage
Louise Mason Bio
Jan Schulte-Hillen
Just forget about him
We had a lot of fun
Son, do your own thing.
Jan Schulte-Hillen Bio
Lynette Rowe
A deadly silence
Caring for Lynnette
A class action law suit
Lynette Rowe Bio
Paul Murphy
Doctors pressured to use Thalidomide
A breach birth
Bring that baby home!
Troubled teenage years
There's always a solution
Paul Murphy Bio
Monika Eisenberg
I had to fight to survive
My mother and me
Hadamar - a dark shadow
No Boundaries
Monika Eisenberg and "minor guilt"
Remembering the victims
Monika Eisenberg Bio
ABOUT THE DRUG THALIDOMIDE
Why Thalidomide?
It was supposed to be Safe
Grünenthal Sales Motto "Succeed at any cost"
Their apology came from their lawyers
Distribution & Marketing
Canada
Australia and New Zealand
Austria
Brazil
Germany
United Kingdom
Italy
Ireland
Japan
Spain
Sweden
United States
Current Uses
A new treatment for leprosy
Thalidomide and Leprosy
A huge Thalidomide comeback
Celgene and Thalidomide
Thalidomide a big money maker
Reaction To The Crisis
"Wonder drug" or baby killer?
Reminiscent of the Nazi era
Thalidomide babies killed
Better drug safety laws implemented
Germany
Germany - "A Single Pill"
Canada
United Kingdom
USA
Australia
A Cautionary Tale
ABOUT GRÜNENTHAL
Company History
From Soap to Thalidomide
Ex-Nazis find a home at Grünenthal
Sales at all Costs
Minor Guilt for a Major Catastrophe
Contergan exposed by Morley Safer
1968 German Trial
Grünenthal's founder evades trial
1960's German justice-a banana republic?
1968 German trial tactics
Grünenthal claims "minor guilt"
Unveiling the German trial documents
2012 Apology
Grünenthal finally apologizes
Grünenthal's 2012 Apology
Reactions to Grünenthal apology
Apology comes from the heart
A bronze statue
A visit to the statue
OTHER NOTABLES
Historical Figures
Frances Kelsey
William McBride
Widukind Lenz
Carl-Hermann
Hermann Wirtz, SR
Heinrich Mückter
Otto Ambros
Others
Michael Magazanik
Martin Johnson
Peter Gordon
Linde Schulte-Hillen
Sir Harold Evans
TIMELINE
TIMELINE
1939
:
Scientists discover that a drug can pass through the placenta and damage a fetus
1946
:
Chemie Grünenthal GmbH is founded
1947
:
Grünenthal mainly manufactures antibiotics
Winter, 1954
:
Keller and Kunz synthesize new compound later to be called Thalidomide
April, 1954
:
Grünenthal obtains a 20 year patent for K 17
1955
:
Thalidomide or K17 is tested on animals
1955
:
Thalidomide or K 17 is tested on humans
June, 1955
:
K 17 “is ready to go on the market”
October 21, 1955
:
An expert recommends that tests should be done over a period of at least 9 to 12 months
December 15, 1955
:
Thalidomide is a substance without “undesirable side effects”
March, 1956
:
Dr. Piacenza writes about “light paresthesia” (“pins and needles”) in connection with K 17
July 10, 1956
:
The NRW Department of Health approves the sale drugs containing of Thalidomide
August, 1956
:
Paper on thalidomide talks about its “sedative effect” and its “extreme non-toxicity”
December 25, 1956
:
The first known Thalidomide baby is born
July 5, 1957
:
Grünenthal asks Bonn University prof to include K 17 in pregnant women test
September 2, 1957
:
Thalidomide gets the name “Contergan” for the German market
September 26, 1957
:
Ads about Contergan are to focus on its sensational “absolute non-toxicity” and “safeness”
October 1, 1957
:
Contergan is put on the West-German market
December, 1957
:
“Unrest and states of excitements” cease to be mentioned
1958
:
Contergan is highly advertised
1958
:
Thalidomide sample pills distributed in the US
March 3, 1958
:
Doctors complain about the wording “absolute non-toxic”
April, 1958
:
Thalidomide sold in Great Britain under the trade-name Distaval
August 1, 1958
:
Grünenthal uses unrelated test results to promote the safety of Thalidomide for pregnant women
August 26, 1958
:
Report on difficulties in walking
1959
:
Growing critical voices
1959
:
Thalidomide under brand names is available as samples in Canada
January, 1959
:
Thalidomide is advertised in a journal about obstetrics and gynecology
January, 1959
:
1959 - USA
March, 1959
:
Complaints about cold feet and hands
June 23, 1959
:
1959 - Canada
July 14, 1959
:
A consumer believes his paresthesia is connected to Contergan
August, 1959
:
More cases of polyneuritis
August 17, 1959
:
Grünenthal doesn’t take growing number of complaints seriously
October 3, 1959
:
Dr. Voss alerts Grünenthal about nerve damage
October 15, 1959
:
Sievers and Werner are lying again
November 27, 1959
:
Voss informs Grünenthal about more cases of polyneuritis and clearly warns about a possible toxicity
November 27, 1959
:
More warnings on that same day
December 30, 1959
:
Dr. Werner and Dr. Sievers lie again
January 14, 1960
:
Contergan is “devil’s work”
February 23, 1960
:
“Contergan causes damage”, according to a neurologist
March 1, 1960
:
Contergan is the most-sold sedative in Germany
March 8, 1960
:
Once again Grünenthal denies having heard of cases of polyneuritis.
April, 1960
:
A Grünenthal representative starts visiting the Ministry of Interior in NRW
April, 1960
:
Grünenthal visits Voss trying to influence him
April 14, 1960
:
Dr. Mückter says “everything needs to be done to prevent the prescription requirement”
May 1, 1960
:
Neurologist Voss publicly talks about nerve damage
Summer, 1960
:
June to October 1960
August 10, 1960
:
Linde Schulte-Hillen takes one pill of Contergan
September 8, 1960
:
1960 Canada
September 12, 1960
:
1960 USA
Fall, 1960
:
Defendants assume the “likeliness” of the nerve damaging effects of Contergan
October, 1960
:
Some hospitals stop giving out Thalidomide
November, 1960
:
The net sales revenue for Contergan reaches 1,215,600 Marks
November, 1960
:
A note that warns about nerve damage is included in the instruction leaflet
November 17, 1960
:
“For Contergan we fight to the last breath.”
November 22, 1960
:
Notice of compliance from the Canadian Food and Drug Directorate
November 24, 1960
:
Pharmacist inquires about malformations
December, 1960
:
"Everything is done to protect our ‘eyeball’"
December 31, 1960
:
First publication about Thalidomide and nerve damage
1961
:
McBride informs Distillers about three malformed babies born in his care
January, 1961
:
Contergan sales in Germany reach their highest point
January, 1961
:
Certainty that Contergan is responsible for nerve damage
January 16, 1961
:
Negative articles about Contergan "are to be prevented"
January 17, 1961
:
Grünenthal suppresses knowledge of reports about damaged babies and children
February 15, 1961
:
Voss thinks nerve damage is irreversible
February 27, 1961
:
Dr. Sievers and Dr. Werner say Contergan doesn’t cause damage
March, 1961
:
Kelsey reads Florence’s letter in the British Medical Journal
April 1, 1961
:
Thalidomide enters Canadian market
April 21, 1961
:
A Grünenthal sales rep makes fun of patients at psychiatric ward who do not notice their nerve damage
May, 1961
:
Dr. Frenkel and others publish articles about nerve damage caused by Contergan
May 11, 1961
:
Kelsey asks if Thalidomide can harm a fetus
May 26, 1961
:
Grünenthal revises package leaflet for Thalidomide
June, 1961
:
Lenz and Schulte-Hillen collect evidence in Northern Germany
June 26, 1961
:
Prescription requirement for Thalidomide containing preparations recommended
June 27, 1961
:
Randolph Reginald Warren is born
Summer, 1961
:
Grünenthal wonders if Thalidomide can pass the placenta
August 1, 1961
:
Prescription requirement is introduced, but only in three federal states
August 16, 1961
:
Grünenthal pays compensation to patients with nerve damage
September, 1961
:
The first article about the increasing numbers of malformed babies is published
September 26, 1961
:
FDA wants pregnancy warning included in instruction leaflet
October, 1961
:
Grünenthal informed about a malformation on a newborn possibly connected to Thalidomide
October, 1961
:
Contergan likely responsible for the malformations
October 3, 1961
:
Thalidomide disturbs bone growth in chickens
November 15, 1961
:
Lenz phones Grünenthal, demanding Thalidomide be taken off the market immediately
November 17, 1961
:
Dr. Lenz sends summary of his observations to Grünenthal
November 19, 1961
:
Lenz publicly talks about his suspicion
November 20, 1961
:
Grünenthal executives meet with Lenz in Hamburg
November 20, 1961
:
Grünenthal sends out 66,957 letters to doctors saying their drug was safe.
November 24, 1961
:
Grünenthal is informed about McBride’s warnings in Australia
November 25, 1961
:
The Ministry of the Interior informs several offices in Germany about the new suspicion against Thalidomide
November 26, 1961
:
The newspaper article that finally makes Grünenthal act is published
November 27, 1961
:
Withdrawal of Thalidomide from the West German market
November 30, 1961
:
Experts believe Thalidomide is responsible for malformations
December, 1961
:
By end of 1961, 1800 cases of nerve damage reported to Grünenthal
December 1, 1961
:
Criminal charges against Grünenthal are filed in Hanover
December 2, 1961
:
Distillers takes Thalidomide off the market in the UK and Australia
December 5, 1961
:
Thalidomide stays on the Canadian market for another four months